High quality recombinant proteins and stable cell lines require high quality DNA. Whether you are interested in gene synthesis, DNA cloning or mutagenesis – our molecular biology department delivers the ideal recombinant gene or plasmid tools for the downstream applications that accelerate your life science innovation.
Fast delivery, direct cloning possible
High quality synthetic genes “Made in Germany”
Free codon and DNA structure optimization – optimize DNA sequences to significantly increase protein expression in any host
No limitations – any sequence in any vector. Accurately and efficiently we fuse your gene into any site on any vector
Collection of various expression vectors instantly available (vector toolbox)
Simply provide us with your desired target sequence and we will take care of the rest. Every synthesis service includes free codon and DNA structure optimization, if desired. We additionally offer comprehensive downstream services that accelerate your research as DNA subcloning into your own expression vector or in one of our huge vector collection.
Highly individual complex cloning projects possible
Huge collection of various expression vectors instantly available (vector toolbox)
Whether you need DNA cloning of PCR fragments, seamless cloning, sub-cloning, mutagenesis, plasmid purification or general vector construction, we are your one-stop-shop for uncompromising high quality plasmid construction.
Our molecular biology experts can bundle gene synthesis with cloning into the vector of your choice, or you can order DNA cloning projects from templates (plasmid or genomic DNA) you already have. Every other and even complex cloning strategy is possible – ask our experts, we will deliver the best cloning strategy for your individual needs.
Simply provide us with your electronic sequences or your project outline – we will propose a customized quotation.
From gene to cell line – development of stable recombinant cell lines with constitutive or inducible target expression.
From gene to protein – recombinant protein production and purification services. From standard to highly customized solutions.
From gene to manufacturing – development of GMP-compliant high producer cell lines suitable for use from the R&D phase up to successful introduction of your product to the market.
Take your research project to the next level with our tailor-made services for recombinant protein production and for stable cell line development (GMP or non-GMP). Let us know your questions and requests about our DNA synthesis service, we will contact you shortly and provide the ideal solution for your project.
Cytokine-induced interleukin-1 receptor antagonist protein expression in genetically engineered equine mesenchymal stem cells for osteoarthritis treatment. J. Gene Med. 20, e3021. (2018)
Gabner S, Ertl R, Velde K, Renner M, Jenner F, Egerbacher M, and Hlavaty J
The bifunctional flavokinase/flavin adenine dinucleotide synthetase from Streptomyces davawensis produces inactive flavin cofactors and is not involved in resistance to the antibiotic roseoflavin. J. Bacteriol. 190, 1546–1553. (2008)
Grill S, Busenbender S, Pfeiffer M, Köhler U, and Mack M