Stem Cell Characterization Service –Characterization of human induced Pluripotent Stem Cells (hiPSC)
The field of human induced Pluripotent Stem Cell (hiPSC) technology is a promising tool for drug discovery, toxicological in-vitro tests and regenerative medicine.
Since the first generation of hiPSCs, numerous reprogramming techniques have been established. However, the in-vitro process of reprogramming is still not fully understood. Often, the cellular stress, induced by the reprogramming process causes genetic and epigenetic alterations that can change the cellular phenotype and affect the integrity of experiments using these cell lines. It is therefore crucial to establish reliable molecular and functional assays to assess pluripotency and to exclude genetic aberrations due to the reprogramming process.
trenzyme’s routinely performed assays for stem cell analysis include the characterization of cells for their expression of pluripotency markers by immunocytochemistry (ICC) and qPCR, molecular karyotyping and evaluation of their differentiation potential by directed trilineage differentiation.
Process of human induced Pluripotent Stem Cell Characterization Service
Fully Characterized and Ready-To-Use hiPSC Master and Working Stocks
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human induced Pluripotent Stem Cell Characterization & Banking Service
If you are engaged in stem cell research and are reprogramming hiPSC lines or initiating experiments with an unknown hiPSC line, our scientific stem cell experts can provide you with fully characterized and ready-to-use hiPSC master and working stocks. In this way, trenzyme can serve as an extended workbench, offering both time and cost savings.
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