Stem Cell Characterization Service
Characterization of human induced Pluripotent Stem Cells (hiPSC)
The field of human induced pluripotent stem cell (hiPSC) technology is a promising tool for drug discovery, toxicological in-vitro tests and regenerative medicine.
Since the first generation of hiPSCs, numerous reprogramming techniques have been established. However, the in-vitro process of reprogramming is still not fully understood. Often, the cellular stress, induced by the reprogramming process causes genetic and epigenetic alterations that can change the cellular phenotype and affect the integrity of experiments using these cell lines. It is therefore crucial to establish reliable molecular and functional assays to assess pluripotency and to exclude genetic aberrations due to the reprogramming process.
trenzyme’s routinely performed assays to validate your hiPSC lines include the characterization of cells for their expression of pluripotency markers via immunocytochemistry (ICC) and qPCR, molecular karyotyping, as well as the evaluation of their differentiation potential by directed trilineage differentiation.
.
Process of human induced Pluripotent Stem Cell Characterization Service
Fully Characterized and Ready-To-Use hiPSC Master and Working Stocks
What Our Clients Say About Us
trenzyme is one of our preferred service providers for cell line development and molecular biology services. The impressive level of personal customer liaison and the scientific competence are decisive factors for us to cooperate with trenzyme for many years and even to intensify in the area of demanding iPS cell line projects.
Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany
human induced Pluripotent Stem Cell Characterization
& Banking Service
If you are engaged in stem cell research and are reprogramming hiPSC lines or initiating experiments with an unknown hiPSC line, our scientific stem cell experts can provide you with fully characterized and ready-to-use hiPSC master and working stocks. In this way, trenzyme can serve as an extended workbench, offering both time and cost savings.
Our Expert Service Includes:
Your Benefits
From Working With Us
Transparency & Communication
Our dedicated project management will guide your project through every step of the process and keep you constantly informed on the progress. Transparency and high quality service are our mission.
Longstanding Expertise
With the extensive knowledge of our highly qualified scientific experts and with access to a huge network of partners and technologies, we complete your project successfully and efficiently.
Optimized Performance
The culture of iPSC is very challenging especially for less experienced persons. With trenzyme´s long-lasting experience we provide optimized culture condition for your iPSC line
High Quality Standards
As an ISO-certified company working with a LIMS based documentation, all projects are completed following highest standards.
Application Note
Quality Control Portfolio of trenzyme to Ensure Pluripotency and Marker Expression of iPS Cell Line
Tanja Waldmann, PhD
Department Head Advanced Cell SystemsWe would be happy to provide you with support on your cell culture research project. Contact us and let us know your questions and requests to our cell culture services. Our scientific experts will reply shortly.