Cell Based Assay Development Service

With our Cell Based Assay Development Service, trenzyme’s scientific experts bring many years of experience in toxicological and pharmacological assay design. We offer the unique advantage of working with any cell type – from immortalized cell lines to iPSC-derived or primary cells. Simply share your requirements (cell type, biological or technical endpoint) and our team will create a tailored protocol, perform the assay in our laboratories, and deliver reliable, publication-ready data.

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Cell Based Assay Development Service – Save Valuable Time For Your Research Project

Current drug development and toxicological testing strategies can be costly and often have high failure rates in later stages of development. Accordingly, cell-based assays are important tools for screening new drug candidates before moving on to expensive animal model testing. With our Cell Based Assay Development Service, our experienced assay experts are dedicated to accelerating your screening capabilities. With our many years of experience in cell based assay development, you can save valuable time for your research project by outsourcing time-consuming workflows to us.

Pharmaceutical companies use a variety of approaches to drug discovery. Historically, large numbers of compounds have been tested in high-throughput biochemical assays. However, the complexity of disease backgrounds has increased the need for more physiological systems and the use of cell-based assays to predict the response of the organism. trenzyme specialises in cell-based assays using various cell lines and state-of-the-art technologies. Our highly skilled experts are able to develop customized cell-based assays and provide reliable results to help you accelerate your screening capabilities. In addition, together with our stem cell experts, complex predictive and translational in vitro assays can be combined with highly physiological human stem cell-derived cell types to provide advanced compound testing solutions.

Cell Based Assay Development Service<
Main Advantages

  • Benefit from a full technology transfer of your assay or let our assay service develop your assays according to your needs.
  • Development of assays based on basic cell lines, customized cell lines or iPSC-derived cell types.
  • Best starting point for your assay development, drug screening and functional studies
  • Broad expertise in assay development for in-vitro-toxicology and pharmaceutical testing.
  • Wide range of techniques to measure endpoints (FACS, Immunostaining, ELISA, Western blot, qPCR).
  • Our custom cell line development service enables the production of assay cell line and therefore the whole process of cell-based assay development is possible from one-stop.
  • GMP-like documentation available on request.

Process of
Cell Based Assay Development Service

Cell-Based-Assay-Development-Service_Process-Steps

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Your Benefits From Working With Us

trenzyme’s cell-based assay services provide customized solutions for drug discovery, biologics characterization and quality control. We offer a wide range of in vitro cell-based assays, including flow cytometry assays, cell-based binding assays, tailored to your specific research needs. Our expertise ensures reliable and reproducible results, supporting the development of high-quality therapeutics.

With extensive experience in cell-based in vitro assays, we design and optimize cell-based assays for applications such as potency testing, mode-of-action studies, and biomarker analysis. Whether you need cell-based assay examples for early-stage research or validated assays for regulatory submission, trenzyme delivers high-performance solutions.

Let us help accelerate your drug development with our state-of-the-art cell-based assay development services!

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Transparency & Communication

Your project manager keeps you constantly informed on the progress of your project.

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Longstanding Expertise

Since 2000, our highly qualified scientific experts accelerate your innovation.

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Optimized Performance

trenzyme‘s assay service enable a time-saving workflow for your project.

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High Quality Standards

As an ISO-certified company, all projects are completed following high standards.

What Our Clients Say About Us

Logo of trenzyme's customer Breeding Botanicals International

“(…) we have carried out many different projects within trenzyme’s cell-based assay service. We particularly appreciate the fast and excellent communication, (…)”

Dr. K. Berger, breeding botanicals international AG

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Application Note
Cell Based Assay Development Services using a standard cell line: HepG2

Preview of trenzyme´s Application Note: Cell Based Assay Development Service
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Cell Based Assay Development Service FAQs

What techniques do you use to measure endpoints?

We use a wide range of techniques to measure endpoints, e.g. FACS, Immunostaining, ELISA, Western blot and qPCR.

Based on which cell line types can you develop assays?

Our scientific experts can develop assays based on basic cell lines, customized cell lines or iPSC-derived cell types. For this, we use our in-house differentiation protocols with cardiomyocytes, hepatocyte-like cells or neurons for your analysis. Alternatively, you can provide us with your protocol so that after the technology transfer, our experts perform the work using this protocol internally at trenzyme.

Is it possible to order both, assay development and subsequent analysis of compounds?

Yes, our assay experts are delighted to develop an assay according to your needs prior to compound analysis.

What does trenzyme’s cell-based assay development service offer?

trenzyme’s cell-based assay services provide customized solutions for drug discovery, biologics characterization and quality control. We offer a wide range of technical endpoints including flow cytometry assays, PCR and ELISA measurements for our in vitro cell-based assays, tailored to your specific research needs. Our expertise ensures reliable and reproducible results, supporting the development of high-quality therapeutics.

With extensive experience in cell-based in vitro assays, we design and optimize cell-based assays for applications such as potency testing, mode-of-action studies, and biomarker analysis. Whether you need cell-based assays for early-stage research or validated assays for regulatory submission, trenzyme delivers high-performance solutions.

Let us help accelerate your drug development with our state-of-the-art cell-based assay development services!

Which cell-based assays can you perform?

trenzyme can perform any in vitro cell-based assay as long as your specific endpoint can be measured with our modern and state-of-the art technical equipment. We can perform flow cytometry, (RT)-qPCR, ELISAs, reporter assays (colorimetry, fluorescence, luminicence) and fluorescence microscopy. All these technical endpoints can be combined with your desired in vitro cell-based assays.

Which cells do you use for your cell-based assay service?

In principal, we can use any cell line for our in vitro cell based assays. If you want to outsource your specific cell-based assay we organize the technology transfer from your laboratory to ours including your cell line. Due to our long-lasting experience we can culture any cell line you may need for our cell-based assay service.

Which cells / cell lines have you already used for your cell-based assay service?

In the past we used many different cell lines for our in vitro cell based assays. There is a wide range from simple cell lines such as HEK290 over more complex cellular systems (e.g. immortalized myoblasts differentiated to mature skeletal muscle cells) to iPSC-derived cell types such as human microglia that can be used for neuroinflammation cell-based assays.

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Our Advanced Cell System Experts

Department of Advanced Cell Systems

We would be happy to provide you with support on your cell culture research project. Contact us and let us know your questions and requests to our cell culture services. Our scientific experts will reply shortly.

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